Effects of subinhibitory concentrations of antibiotics on virulence factor expression by community-acquired methicillin-resistant Staphylococcus aureus
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چکیده
منابع مشابه
Effects of subinhibitory concentrations of antibiotics on virulence factor expression by community-acquired methicillin-resistant Staphylococcus aureus.
OBJECTIVES To examine the effect of subinhibitory concentrations (sub-MICs) of antistaphylococcal drugs on Panton-Valentine leucocidin (PVL), α-haemolysin (Hla) and protein A (SpA) expression by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). METHODS Five clinical isolates representing the main worldwide CA-MRSA clones were grown with sub-MICs (1/8, 1/4 and 1/2 MIC) ...
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There was no drainage from the lesion. Two more small papules were noted on the buttocks. Physical findings were otherwise unremarkable. Wound culture was positive for methicillin-resistant Staphylococcus aureus (MRSA). Initial treatment with intravenous vancomycin was switched to intravenous clindamycin after culture results showed MRSA. The patient's symptoms resolved after 2 days of treatmen...
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Methicillin-resistant Staphylococcus aureus (MRSA) is no longer only hospital acquired. MRSA is defined as community acquired if the MRSA-positive specimen was obtained outside hospital settings or within 2 days of hospital admission, and if it was from a person who had not been hospitalized within 2 years before the date of MRSA isolation. To estimate the proportion of community-acquired MRSA,...
متن کامل[Community-acquired methicillin resistant Staphylococcus aureus].
Recently, methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a cause of community-acquired (CA) infections among patients without established risk factors for MRSA. CA-MRSA strains mainly cause mild skin and soft tissue infections in otherwise healthy children and young adults, but can also cause severe necrotizing fasciitis and pneumonia. In contrast to nosocomial MRSA, CA-MRSA ...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2013
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/dkt073